Cough response to isocapnic hyperpnoea of dry air and hypertonic saline are interrelated
نویسندگان
چکیده
منابع مشابه
Cough response to isocapnic hyperpnoea of dry air and hypertonic saline are interrelated
BACKGROUND Mechanisms behind asthmatic cough are largely unknown. It is known that hyperosmolar challenges provoke cough in asthmatic but not in the healthy subjects. It has been postulated that isocapnic hyperpnea of dry air (IHDA) and hypertonic aerosols act via similar mechanisms in asthma to cause bronchoconstriction. We investigated whether there is an association between cough response in...
متن کاملA comparison between the airway response to isocapnic hyperventilation and hypertonic saline in subjects with asthma.
We compared the response to isocapnic hyperventilation (ISH), where both cooling and drying of the mucosa occur, with the response to inhaling aerosols of hypertonic saline (HS), where airway osmolarity increases without airway cooling. We studied nine subjects on two days. For ISH, subjects ventilated at 70% of their estimated maximum voluntary ventilation (MVV). For HS, they inhaled aerosols ...
متن کاملIsocapnic hyperpnoea accelerates recovery from isoflurane anaesthesia.
BACKGROUND Hyperventilation should speed up elimination of volatile anaesthetic agents from the body, but hyperventilation usually results in hypocapnia. We compared recovery from isoflurane anaesthesia in patients allowed to recover with assisted spontaneous ventilation (control) and those treated with isocapnic hyperpnoea. METHODS Fourteen patients were studied after approximately 1 h of an...
متن کاملIsocapnic hyperpnoea shortens postanesthetic care unit stay after isoflurane anesthesia.
BACKGROUND We conducted a prospective controlled clinical trial of the effect of isocapnic hyperpnoea (IH) on the times-to-recovery milestones in the operating room (OR) and postanesthetic care unit (PACU) after 1.5 to 3 hours of isoflurane anesthesia. METHODS Thirty ASA grade I-III patients undergoing elective gynecological surgery were randomized at the end of surgery to either IH or the co...
متن کاملAirway responsiveness to hypertonic saline: dose-response slope or PD15?
The result of airway challenge test with hypertonic saline (HS) is expressed as the dose causing a 15% fall in forced expiratory volume in one second (FEV1; PD15). A noncensored measure, such as the dose-response slope (DRS), allows the evaluation of the risk of asthma for subjects with a fall in FEV1 <15%. The aim of this study was to assess the relationship between airway responsiveness to HS...
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ژورنال
عنوان ژورنال: Cough
سال: 2011
ISSN: 1745-9974
DOI: 10.1186/1745-9974-7-8